John Rinn Image
Professor • Leslie Orgel Professor of RNA Science • Marvin H. Caruthers Endowed Chair for Early-Career Faculty
Biofrontiers & Biochemistry
john.rinn@colorado.edu

Office: JSCBB B417
Lab: JSCBB A453

Education

Bachelor's:聽Chemistry, University of Minnesota 1999
笔丑顿:听Molecular Biophysics and Biochemistry, Yale University 2004
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Areas of Expertise

long noncoding RNA, RNA, ncRNA, Bioinformatics & computational biology, Epigenetics, Gene expression & regulation, Genetics

Awards and Honors

  • 2013 Alvin and Esta Starr Associate Professorship
  • 2010 Merkin Next Generation Fellow
  • 听听听听听听听听听听听
  • 2008 Smith Family Foundation Fellowship
  • 2005 Damon Runyon Cancer Foundation Fellowship
  • 2004 Yale University School of Arts and Sciences Commencement Marshall聽
  • 2003 McDougal Fellowship, Yale University, for Professional Development.
  • 2002 AAAS Biovision Fellowship.
  • 1999 Department of Chemistry Honors : Awarded to top 10 chemistry graduates.
  • 1999 Casmir Illunda Award : best senior thesis research and presentation.

Our research bridges computational and experimental sciences to discover new regulatory aspects in the human genome - - Specifically how long noncoding RNA (lncRNA) genes regulate numerous biological processes. We have continually applied and developed many technologies such as single-molecule RNA imaging, RNA-sequencing, Single Cell RNA-sequencing, CRISPR-Display and SNP-CLING. This multifaceted and cross-disciplinary approach is focused on unraveling the molecular modalities underlying RNA biology and in turn how it regulates cell state.聽

Our teaching of University of Colorado Biochemistry Undergraduate and Graduate Students aims to enable all students to perform bioinformatic and data science analyses on ever emerging forms of genome-wide data such as RNA-seq, ChIP-seq, ATAC-seq.

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Scientific Advisory Boards

Articles featuring John Rinn

cell
How does a stem cell know what to become? Study shows RNA plays key role

July 7, 2020

In a study published July 6 CU 麻豆影院 researchers come one step closer to answering that fundamental question, concluding that the molecular messenger RNA (ribonucleic acid) plays an indispensable role in cell differentiation, serving as a bridge between our genes and the so-called 鈥渆pigenetic鈥� machinery that turns them on and off.

Telomeres
The unexpected complexities of TERT, a key cancer driver

Sept. 11, 2019

Telomerase reverse transcriptase (TERT), an enzyme associated with nearly all malignant human cancers, is even more diverse and unconventional than previously realized according to new research by CU Biochem and BioFrontiers' Distinguished Professor Thomas Cech and Professor John Rinn.