This site is an archive for the Center for the Integrative Study of Work in Living Systems (CISW), founded in 2000.聽 Current programmatic information on the integrative study of work in living systems may be found at .

CISW and its members and fellows have developed several cross-disciplinary聽scientific projects and project teams, including:

  • Collaborating on making connections in basic research in mathematics and molecular biology
  • Collaborating in neuroscience and evolutionary biology聽around trade-offs between energy and information in neural and organismal systems
  • Developing empirical and theoretical approaches between molecular biology and neuroscience聽on system effects of aneuploidy on neural function

From collaborative work with research teams, and from聽research and practice on human work performance, CISW has developed practices with which investigators can enhance how their groups perform the Work of Research:

  • Working groups across departmental boundaries for research grant development.
  • Work process analysis for experiments,聽scaling, collaborative work, especially by identifying processes at risk for unanticipated changes.
  • Selection of graduate students and team members聽into research teams, including teams involving multiple institutions.
  • Changes in postdocs (and other lab personnel) often change experimental聽work processes and protocols in unanticipated and undocumented ways. 聽Developing training for research team members in specific experimental work processes provides a method both for effective training and for ensuring continuity in the lab when postdocs change.
  • Early research topic development frequently involves generating high rates of false negatives. 聽Training graduate students (and mentors) in the risks of early-stage false negatives helps maintain productive idea generation, while also reducing later-stage dead-ends, frustration, and time without results.