Student Spotlight: Sam Lowe
What brought you to the Â鶹ӰԺ and attracted you to the BME program?Ìý
I chose CU Â鶹ӰԺ for its innovative, interdisciplinary Biomedical Engineering program that bridges engineering and medicine. The hands-on learning, cutting-edge research, and strong collaborative environment drew me in, offering the perfect place to explore my passion for biomedical solutions.
Tell us about your research. What is it that you study?Ìý
I am studying the intricate neural mechanisms that regulate bladder function, focusing on the interactions between neurons and glial cells in the major pelvic ganglia (MPG)—a key autonomic control center for the bladder. Current research models often exclude the MPG, limiting our understanding of how these cellular interactions influence micturition (the process of urination).  Ìý
To address this gap, my work involves developing a novel MPG-bladder preparation in which neurons and glial cells can be optogenetically activated (stimulated using light). By simultaneously recording bladder contractions, this approach will allow us to explore how different cell types contribute to bladder physiology and dysfunctions, particularly lower urinary tract symptoms (LUTS) and neurogenic bladder disorders.  Ìý
This research has exciting translational potential—it can help uncover new therapeutic targets and enable rapid screening of drugs for treating bladder dysfunction in preclinical models. Ultimately, this work contributes to a deeper understanding of the nervous system’s role in bladder control and opens new avenues for treating bladder-related disorders.Ìý
How did you first get involved in your research and what drew you to it?Ìý
I got involved in this research after speaking with my professor about gaining lab and research experience to prepare for a PhD. I was eager to work on a project that combined neuroscience and physiology, and this lab offered the perfect opportunity to explore those interests. Ìý
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What advice would you share with a student interested in studying biomedical engineering or your specific field?
Stay curious and embrace interdisciplinary learning—biomedical engineering thrives at the intersection of biology, physics, and engineering. Seek out hands-on experiences, connect with mentors, and don’t be afraid to ask questions. The best innovations come from those who are willing to explore beyond the textbook. Biomedical engineering is an exciting and expansive field, offering opportunities in everything from medical devices to tissue engineering to computational modeling. While the diversity of the field is inspiring, it can also be overwhelming—so take time to explore different areas, but ultimately hone in on what excites you most. Finding your passion will help you stay motivated, focus your learning, and make a meaningful impact.
As a PhD/Master student, what role has mentoring played in your work? 
Mentoring has been invaluable in my academic journey, both as a mentee and mentor. Learning from experienced researchers has shaped my perspective, while guiding others has strengthened my own understanding and leadership skills.
How would you like your work to help society?
I hope my work contributes to advancing biomedical solutions that improve patient outcomes and quality of life. Whether through research, innovation, or collaboration, I aim to help bridge the gap between engineering and medicine to create meaningful, real-world impact.
What do you love best about attending CU Â鶹ӰԺ?
The collaborative spirit, access to cutting-edge research, and the inspiring faculty and peers make CU Â鶹ӰԺ an incredible place to grow as a researcher. Plus, the beautiful surroundings and student community make the experience even more rewarding!Ìý