麻豆影院 researcher Karolin Luger, a distinguished professor of biochemistry and Jennie Smoly Caruthers Endowed Chair of Biochemistry, has been awarded the 2023 World Laureates Association Prize in Life Science or Medicine.

The award, announced Thursday morning in Shanghai, China, recognizes Luger鈥檚 deep body of research 鈥渆lucidating the structure of the nucleosome at the atomic level, providing the basis for understanding chromatin, gene regulation and epigenetics,鈥� the award citation notes.

The  (WLA) Prize is an international science prize established in 2021 that recognizes researchers and technologists worldwide for their contributions to science. It aims to 鈥渟upport global science and technology advancement, address the challenges to humanity and promote society's long-term progress,鈥� according to the WLA.

Read more about this year's WLA Prize...

Also featured in local media: Colorado Arts and Sciences Magazine and 

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With a vote by the CU Board of Regents, the University of Colorado recently recognized Karolin Luger as a Distinguished Professor鈥攖he highest honor bestowed upon faculty across the system鈥檚 four campuses.  

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Briana Aboulache and Karolin Luger win Howard Hughes Medical Institute Gilliam fellowship, which looks to build a more inclusive scientific environment

Briana Aboulache, a graduate student at the 麻豆影院, and her advisor, Biochemistry Professor Karolin Luger, have won a significant fellowship that aims to advance diversity and inclusion in science.

Aboulache and Luger are among 50 student-advisor duos to win a 2021 Howard Hughes Medical Institute (HHMI) Gilliam fellowships, the . The awards are bestowed to graduate students conducting outstanding research and their advisers, and are targeted toward those who are committed to building a more inclusive scientific ecosystem. 

Briana Aboulache

For up to three years, each adviser-student pair will receive an annual award totaling $50,000. This year鈥檚 fellows鈥� research includes studying how malaria parasite broods destroy red blood cells and trying to identify the source of pollution behind harmful algal blooms in a river used by the Seneca Nation and other communities.

鈥淚 was struck by the scientific maturity of these students,鈥� says David Asai, HHMI鈥檚 senior director for science education. 

鈥淭hey鈥檙e all doing great science, and they can talk about it in a way that people understand.鈥� What鈥檚 more, he adds, their advisers are serious and thoughtful about their role as mentors and their plans to create healthy academic cultures at their universities.

Aboulache is pursuing a PhD in biochemistry and is in her third year in Luger鈥檚 lab. She studies how the chromatin remodeling protein SMARCAD1 interacts with nucleosomes during DNA repair, transcription and replication.

Luger said she has always believed that training the next generation of scientists is her most important and primary task. 

We should expect to see talented students and scientists from underrepresented groups on college campuses and across all of science.鈥�"

鈥淥ne really good way to increase the diversity of scientists at all levels, be that academia, industry or outreach, is a tailored mentoring approach,鈥� she said, adding: 鈥淚 am so grateful to HHMI for recognizing this need and for providing me with the tools to become a better and more inclusive mentor.鈥� 

She said she looks forward to meeting other colleagues and their students to make the scientific endeavor better reflect the general population.

Aboulache said she was 鈥渆xtremely honored鈥� to receive the Gilliam Award. 鈥淚 am excited to be surrounded by great scientists, leaders and activists aimed at producing cutting-edge research while also increasing diversity in the sciences.鈥�

Aboulache praised Luger as an exemplary role model. 鈥淪he is an excellent, highly motivated leader who produces remarkable science and also cares deeply about her students and lab members.鈥� 

鈥淎s I continue to develop and mature as a scientist, I look forward to mentoring students in the lab and the classroom, and hope to one day go into teaching. I plan on instilling the valuable and effective leadership strategies that have helped me develop as a scientist to empower others to succeed,鈥� Aboulache said. 

Noting her own work to foster an inclusive environment in science, Aboulache said she hopes to continue creating a work environment 鈥渨here people take the time to understand each other鈥檚 point of view, build trust, and align in a shared mission to perform revolutionary science that is accessible to everyone.鈥� 

Karolin Luger

She added: 鈥淢y goal is to excite future generations about science and empower diverse groups to make meaningful impacts on the world.鈥�

Mentorship is a Gilliam hallmark, says the HHMI, that鈥檚 sparking a 鈥渃ultural shift鈥� on campuses. Since its inception in 2004, HHMI鈥檚 Gilliam Program has worked to ensure that students from populations historically excluded and underrepresented in science are prepared to become scientific leaders. 

To retain as many of these students as possible in PhD programs, it鈥檚 crucial to provide high-quality mentoring, as well as financial support, an inclusive lab environment and a supportive community, Asai says.

In total, the Gilliam Program has now selected 351 fellows, and, from 2015 to 2021, the program has focused heavily on developing academic mentors. To date, the program, in collaboration with the Center for the Improvement of Mentored Experiences in Research (CIMER), has trained 199 mentors on how to create an environment that helps students of all backgrounds feel like they belong鈥攊n the lab and in science. 

Gilliam advisers participate in a year of mentor development activities that emphasize cultural awareness, including monthly online training and two in-person workshops at HHMI headquarters in Chevy Chase, Maryland. Together, the activities teach advisers how to listen and engage across cultures.

By training mentors and supporting the growing Gilliam community, the program aims to make the academic environment inclusive so that students see themselves in science. Eventually, Asai hopes, this will increase the diversity of scientists at the faculty level. 

鈥淒iversity in science should be the norm,鈥� he says. 鈥淲e should expect to see talented students and scientists from underrepresented groups on college campuses and across all of science.鈥�

Members of the Gilliam community also support each other outside of the annual meeting. Fellows regularly celebrate one another鈥檚 successes and provide updates on their career journeys on social media. 

And since 2017, the program has maintained a listserv where alumni and fellows can ask for career advice and post job opportunities. Even though some have never met in person, members of the community often answer questions and share their experiences. 

HHMI created the Gilliam Fellowships for Advanced Study in honor of the late James H. Gilliam, Jr. A charter trustee of HHMI, Gilliam was a respected business and civic leader who spent his life nurturing excellence and diversity in science and education.

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Some of the most commonly used drugs for treating hereditary breast and ovarian cancers may not work the way we thought they did, according to new CU 麻豆影院 research.

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The 麻豆影院 will be one of four national centers designed to advance the application of cryoelectron tomography (cryoET), which helps visualize in 3-D the fine-structure of intact cells and tissues, the National Institutes of Health announced (NIH) today.

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Researchers have discovered the structure of the FACT protein鈥攁 mysterious protein central to the functioning of DNA

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